Are there similarities between Parkinson's disease, Lewy body disease and CADASIL?


(Prof. Chabriat) "CADASIL is a disease of small vessels and can be the cause of small cortical infarctions. These infarctions are located in the central gray nuclei (basal ganglia), an area at the center of the brain which controls motor functions. Patients with CADASIL may have walking disorders, along with a slowing down of movements, and some doctors may say that there is a resemblance to Parkinson's disease. But this is not Parkinson's disease and it has nothing to do with it. In the case of Parkinson's disease, the basal ganglia don’t work well and don’t produce enough Dopamine. Parkinson's disease is not a disease of the vessels. Lewy bodies may accumulate in the basal ganglia in Parkinson's disease and there are some other degenerative diseases with these bodies more dispersed in the brain, which is not the case with CADASIL."
CADASIL FRANCE Annual General Meeting - April 2017


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