“In 2008 you said, regarding statins," it is desirable, based on current level of knowledge, to consider statins only in the presence of exceedingly high cholesterol ... ". What is your opinion about them now (in 2012) and why?"


Prof. Bousser indicates that a study on people with no cholesterol, no history of myocardial infarction and having had a cerebral infarction (not specifically related to CADASIL) showed that statins reduced the risk of infarction. But statins have been mainly developed for atherosclerosis (condition in which an artery wall thickens as a result of the accumulation of fatty materials such as cholesterol) and Prof. Chabriat confirms his position: He does not recommend statins, except for high cholesterol.

Date: March 2012

CADASIL General Meeting (www.CADASIL.com)


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