Questions and Answers

This section was created so you can view questions and answers to some common queries about CADASIL.

If you cannot locate your answer, please contact us so we can present your question on to our Scientific Advisory Committee.

Current Questions:

Does hemplegic migraines have anything to do with CADASIL?
Familial hemiplegic migraine is not related to CADASIL, it is not a vascular disorder and it is caused by mutations of other genes. However, CADASIL is increasing the risk of migraine with aura (40% have migraine with aura) and hemiplegic migraine can be observed in CADASIL patients as other types of migraine with aura. (2016)

If a patient had a skin biopsy and it was positive but the blood test was negative, what should the patient do? The first step is to check the results of skin biopsy and to ensure that granular osmiophilic material is present. If this is the case, searching all mutations using a complete screening of the NOTCH3 gene is needed. (2016)

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