<CADASIL Testing Locations CADASIL Together We Have hope - Official Site

CADASIL Testing Locations

Testing sites for CADASIL around the world.  If you use any of these sites, please let them know you were referred by us. If you know of any other locations,
please e-mail us info@cadasilfoundation.org

U.S.A England Netherlands
Austria France Portugal
Canada Germany South Korea
Czech Republic Israel  Spain

Athena Diagnostics, Inc.
Four Biotech Park
377 Plantation Street
Worcester, MA 01605
Phone: 1 (800) 394-4493
or 1 (508) 756-2886 (For callers outside the US and Canada)


Thank you to Athena Labs for working with us on having patients diagnosed correctly at an affordable price.

Note for U.S.A. patients: The Affordable Care Act (ACA) , a law that was passed in 2010, defines certain health services as "Essential Health Benefits ," which must be covered by all health plans.  What is actually covered may 
vary by state  as some states already require coverage of the federally mandated services.

Genetic testing
may be necessary for many reasons, including for preventive, reproductive, or life planning measures. You may be reluctant to have these tests done because your insurance provider might not cover the costs and you don’t want to pay out-of-pocket. Ultimately, genetic testing can be very important in figuring out a health condition, and it’s important for you to do everything that you can to maximize your health.

Complete CADASIL Evaluation

Type of Disorder: Cerebrovascular Disease
Typical Presentation: Hereditary cause of stroke, dementia, migraine with aura, mood disorders
Disease(s) tested for: CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy)
Test Details
Test Code: 421
Informed Consent Required: Yes
Special Notes: Athena sequences all 23 exons where all known mutations for CADASIL have been found.
Technical Information
Utility: Detects mutations in the Notch3 gene
Methodology: Polymerase Chain Reaction (PCR) and DNA sequencing
Reference Value: No mutation detected
Patents: 6,995,257, 6,537,775, 7,138,234
CPT Coding
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
CPT 2013: 81406(1)
Shipping Considerations
Please label each specimen tube with two forms of patient identification. These forms of identification must also appear on the requisition form.
Preferred Specimen Requirements
Type: Whole blood
Minimum Volume: 10ml
Collection Tube: Lavender top (EDTA)
Storage Conditions: Refrigerate, avoid freezing
Shipping Conditions: Room temperature. Ship within 24 hours, Monday -Thursday only.
Test Turnaround: 21-28 days


Praxis for Humangenetik
acharzt für Humangenetik und Medizinische Biologie
Brünnlbadgasse 15, Tür 6, A-1090 Wien
Vienna, Austria
Tel.: 01/95 80 164 oder 0664 42 622 58
Fax: 01/95 80 164
E-mail: humangenetik@gencik.com


Molecular Diagnostic Laboratory 
Victoria Hospital, Room B10-123 
London Health Sciences Centre 
800 Commissioner’s Rd E. 
London, Ontario, Canada 
N6A 5W9

Contact Information:

Ph: 519-685-8122 
Fax: 519-685-8279


Alberta Children's Hospital
Molecular Diagnostic Laboratory
Calgary, Alberta, Canada
email: dna.lab@calgaryhealthregion.ca
phone: (403) 943-7026 fax: (403) 943-7624 
Molecular Genetics Laboratory
Vancouver, BC, Canada
email: moleculargenetics@cw.bc.ca
phone: (604) 875-2852 fax: (604) 875-2707 
BC Children's and BC Women's Hospitals
Molecular Genetics Laboratory 
Molecular Diagnostic Laboratory
Room E3-304 Westminster Tower, WC
London Health Sciences Centre
800 Commissioner’s Rd E.
London, Ontario, Canada
N6A 4G5
Ph: 519-685-8122 and Fax: 519-685-8279
E-mail: ainswort@uwo.ca oralan.stuart@lhsc.on.ca 
Health Sciences Centre
Molecular Diagnostic Laboratory
Winnipeg, Manitoba, Canada
email: mgibb@hsc.mb.ca


Charles University in Prague -
First Faculty of Medicine and General University Hospital
Institute of Inherited Metabolic Disorders
Praha, Czech Republic, Viktor Kozich, MD, PhD

Professor Hugh Markus
Consultant Neurologist
St. George’s Hospital 
Blackshaw Road 
Tooting, London SW17 0RE
email: info@CADASIL.co.uk

Royal Devon and Exeter Hospital
Department of Molecular Genetics 
Sian Ellard, BSc, PhD, FRCPath
Sheffield Children's NHS Foundation Trust
Sheffield Diagnostic Genetics Service 
Ann Dalton, PhD, FRCPath

CERVCO Secretariat 
Mrs. Solange Hello
Tel: 01 49 95 25 91
E-mail: secretariat.cervco@lrb.aphp.fr
Paris, France

Contact information of the managing director:
Dr. Alfred C. Looman PhD. Gene Analysis Service
GmbH, Grainauer Str. 12,
10777 Berlin, Germany phone: +(49)-30-84707430
Website at www.gene-analysis-service.de 
Germany Neurologisches Forschungshaus
Marchioninistr.23 Tel.: +49- 89- 7095- 4810, 7801, 7805, 4813 

Prof Daniela Steinberger, MD, PhD
bio.logis Center for Human Genetics 
Frankfurt, Germany

Prof Dr Carsten Bergmann, MD, PD; Prof Dr Hanno Bolz, MD
Center for Human Genetics, Ingelheim
Bioscientia GmbH  Ingelheim, Germany

Synlab MVZ Humane Genetik München
Labor für Humangenetik 
Dr Claudia Nevinny-Stickel-Hinzpete 
Laboratory for Molecular Diagnostics
Synlab MVZ Humane Genetik München
Labor für Humangenetik 

Dr Claudia Nevinny-Stickel-Hinzpeter
München, Germany 
Christoph Ehlers; Prof Arndt Rolfs, MD;
Prof Dr Jürgen Kohlhase, MD
Centogene GmbH

The Rare Disease Company 
Rostock, Germany
Dr Hagen Pommerenke, PhD
Diagenom GmbH
Medical Genetics Laboratory 
Rostock, Germany

GGA - Galil Genetic Analysis 
Prof Stavit Allon-Shal
Pronto Diagnostics Ltd.
ProntoLab - MLPA Lab 
Dr Ruth Shomrat
Tel Aviv, Tel Aviv, Israel

Leiden University Medical Cente
Laboratory for Diagnostic Genome Analysis
Egbert Bakker, Phd
Leiden, Netherlands

CGC Genetics
Purificacao Tavares, MD, Phd; Paula Rendeiro, CTO
Porto, Portugal

Samsung Medical Center
Department of Laboratory Medicine and Genetics
Sun Hee Kim, MD, PhD; Dr Hee-Jin Kim, MD, PhD; Jong-Won Kim, MD,
PhD; Soo-Youn Lee, MD, PhD; Dr Chang-Seok Ki, MD, PhD

Instituto De Medicina Genómica

Javier Garcia-Planells, Phd; Dr Carlos Ruiz, Phd; María Garcia-Hoyos, Phd
Paterna, Comunidad Valenciana, Spain
Sistemas Genomicos SL
Medical Genetics Unit
Dra Trinidad M. Alberola-Pons, Phd; Dr Sonia Santillán,
MD, Phd; Dr Ana Blanco, Phd, Pharmd; Diego Cantalapiedra,
Bsc, Msc; Dra Lucia Pérez, Phd, Bsc; Dr Miquel Tuson, Phd, Biol Sci D
Paterna, Comunidad Valenciana, Spain